Bio-protocol Webinars|标签保留扩展显微镜（LR-ExM）的成像与降噪
扩展显微镜（Expansion Microscopy, ExM）由Ed Boyden团队于2015年首次推出，通过将生物样品包埋到具有超强吸水膨胀能力的聚合物中，将样品均匀撑大，使得普通荧光显微镜也能实现超分辨成像。自发明以来，ExM已经用许多不同类型的生物样品进行了测试。然而使用ExM面临的主要挑战是聚合和消化过程中的荧光信号损失。最近开发的标签保留扩展显微镜(Label Retention Expansion Microscopy, LR-ExM)解决了三功能锚(trifunctional anchors)的问题。
本次研讨会我们很荣幸地邀请到加州大学旧金山分校的研究科学家、陈·扎克伯格生物中心研究员Xiang Zhao博士和陈·扎克伯格生物中心的Ahmet Can Solak工程师作为演讲嘉宾，加州大学欧文分校助理教授Xiaoyu Shi博士作为主持人和大家探讨使用Aydin软件进行去噪的标签保留扩展显微镜，会议主要围绕以下三个方面讨论。
用标签保留扩展显微镜对细胞进行超分辨率成像
使用Aydin去噪提高LR-ExM图像的质量
介绍Aydin软件以用于处理大多数生物成像数据
届时有～30分钟的现场答疑环节 ，欢迎大家参与！
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